GLP-1 Weight Loss Drug Prices in 2026: Wegovy, Ozempic, Mounjaro Compared
Manufacturer self-pay prices for Wegovy, Ozempic, Zepbound and Mounjaro, checked on NovoCare and LillyDirect on September 24, 2026, plus the Medicare GLP-1 Bridge and what the end of the FDA shortages means for compounded versions.
Written by FairVisitHealth Editorial Team · Healthcare Pricing Analysts
Reviewed by the FairVisitHealth Editorial Team (Pricing & Billing Data Review). Not medical advice. Data sourced from CMS, HRSA, and hospital price transparency filings.
Key Takeaways
- On September 24, 2026, NovoCare listed Wegovy pens at $349/month self-pay and Wegovy pills from $149/month
- LillyDirect listed Zepbound from $299/month (2.5 mg), rising to $449/month for 7.5 mg to 15 mg when refilled within 45 days
- The FDA declared the tirzepatide and semaglutide shortages resolved on December 19, 2024 and February 21, 2025; compounding grace periods ended in 2025
- Medicare's GLP-1 Bridge offers eligible Part D enrollees a $50 monthly copayment from July 1, 2026 through December 31, 2027
- Novo Nordisk's commercial savings offer caps savings at $100 per month
Prices checked on the manufacturers' own websites on September 24, 2026. Manufacturers can change or end these offers at any time, so confirm the price before you order.
The price of brand-name GLP-1 medication now depends mostly on how you pay: self-pay through a manufacturer pharmacy, a commercial insurance plan with a savings card, or Medicare. This guide lists the manufacturer self-pay prices we could verify, and what changed for compounded versions and Medicare.
Manufacturer self-pay prices
| Medicine | Maker | Approved use (maker's page) | Self-pay price, checked September 24, 2026 |
|---|---|---|---|
| Wegovy pill (semaglutide tablets) | Novo Nordisk | Weight management and cardiovascular risk reduction | $149/month (1.5 mg), $199/month (4 mg), $299/month (9 mg and 25 mg) at NovoCare Pharmacy |
| Wegovy pen (semaglutide injection) | Novo Nordisk | Weight management and cardiovascular risk reduction | $349/month (0.25 mg to 2.4 mg). New patients: $199/month for the first 2 monthly fills of 0.25 mg or 0.5 mg, offer through December 31, 2026. Wegovy HD 7.2 mg: $399/month |
| Ozempic pen (semaglutide injection) | Novo Nordisk | Type 2 diabetes | $349/month (0.25 mg, 0.5 mg, 1 mg), $499/month (2 mg). New patients: $199/month for the first 2 fills of 0.25 mg or 0.5 mg, through December 31, 2026 |
| Zepbound (tirzepatide) KwikPen or single-dose vial | Eli Lilly | Weight management | $299/month (2.5 mg), $399/month (5 mg), $449/month (7.5 mg to 15 mg) if you refill within 45 days. Otherwise $499 (7.5 mg) or $699 (10 mg to 15 mg) |
| Mounjaro (tirzepatide) | Eli Lilly | Type 2 diabetes | Self-pay starting at $499/month through LillyDirect. Lilly lists the list price (wholesale acquisition cost) as $1,112.16 per fill |
Wegovy and Zepbound are the brands labeled for weight management. Ozempic and Mounjaro are labeled for type 2 diabetes, which matters for insurance coverage and for the Medicare program below.
Compounded semaglutide and tirzepatide after the shortages
Compounding pharmacies were able to make copies of these drugs while they were on the FDA drug shortage list. That period is over:
| Drug | FDA declared shortage resolved | 503A pharmacy grace period ended | 503B outsourcing facility grace period ended |
|---|---|---|---|
| Tirzepatide | December 19, 2024 | February 18, 2025 | March 19, 2025 |
| Semaglutide | February 21, 2025 | April 22, 2025 | May 22, 2025 |
The FDA says compounded drugs should only be used when a patient's medical needs cannot be met by an FDA-approved drug, and it has published warnings about fraudulent compounded products, counterfeit Ozempic, and dosing errors with compounded semaglutide. If a seller offers "compounded semaglutide" today, ask what medical need it meets that the approved product does not.
Medicare: the GLP-1 Bridge
From July 1, 2026 through December 31, 2027, Medicare runs a temporary demonstration called the Medicare GLP-1 Bridge:
- Cost: a $50 monthly copayment for a one-month supply. The Part D deductible does not apply, the copayment does not count toward your Part D out-of-pocket costs, and Extra Help does not reduce it.
- Covered drugs, for weight management only: Foundayo (tablet), Wegovy (injection or tablet), and Zepbound KwikPen. Zepbound vials and single-dose pens are excluded.
- Who qualifies: adults 18 or older with Part D coverage and a BMI of 35 or more; or a BMI of 30 to 34.9 with diastolic heart failure, uncontrolled hypertension, or chronic kidney disease stage 3a or higher; or a BMI of 27 to 29.9 with prediabetes, a previous heart attack or stroke, or symptomatic peripheral artery disease.
- Who does not: people whose Part D plan already covers a GLP-1 for them, and people with type 2 diabetes, moderate-to-severe sleep apnea, or fatty liver disease, per Medicare.gov.
Commercial insurance and savings cards
Novo Nordisk's savings offer lets commercially insured patients pay as little as $25 for Wegovy, with savings capped at $100 per month, for pickup at a local pharmacy. Government plan beneficiaries are excluded. The cap means the card does little if your plan does not cover the drug. Lilly states that people with Medicaid, Medicare, Medigap, DoD, VA, or TRICARE are not eligible for the Mounjaro Savings Card.
How to choose a way to pay
- On Medicare Part D? Check the GLP-1 Bridge criteria above first. If you qualify, $50 per month is lower than any self-pay price in the table.
- Commercially insured? Ask your plan whether it covers the drug for your diagnosis. If it does, the manufacturer savings card applies. If it does not, the $100 monthly savings cap means self-pay is usually the comparison to make.
- Paying cash? Compare the manufacturer prices in the table for the dose you will actually reach, not just the starting dose. Zepbound's lower price for higher doses depends on refilling within 45 days.
- Considering a compounded product? Ask the prescriber what medical need it meets that an approved product does not, which is the FDA's standard. Buy only from a state-licensed pharmacy that fills your prescription.
- Interested in research? Search ClinicalTrials.gov for recruiting obesity studies near you, and ask each study team what participation costs.
You can compare current GLP-1 prices by pharmacy on our GLP-1 price page.
Sources
- NovoCare Pharmacy, Wegovy self-pay prices and Wegovy price guide (PDF). Checked September 24, 2026.
- NovoCare Pharmacy, Ozempic self-pay prices and indications. Checked September 24, 2026.
- LillyDirect, Zepbound self-pay prices and Mounjaro self-pay prices. Checked September 24, 2026.
- Lilly, Mounjaro pricing information (list price from a January 1, 2026 source). Checked September 24, 2026.
- U.S. Food and Drug Administration, FDA clarifies policies for compounders as national GLP-1 supply begins to stabilize and FDA's concerns with unapproved GLP-1 drugs used for weight loss. Checked September 24, 2026.
- Medicare.gov, Weight loss drugs, and CMS, Medicare GLP-1 Bridge. Checked September 24, 2026.
Related Cost Guides
Frequently Asked Questions
How much is Wegovy without insurance?
On September 24, 2026, NovoCare Pharmacy listed Wegovy pens at $349 per month for doses from 0.25 mg to 2.4 mg, with new patients paying $199 per month for the first two fills of 0.25 mg or 0.5 mg through December 31, 2026. Wegovy pills were $149 to $299 per month depending on dose.
Can I still get compounded semaglutide?
The FDA declared the semaglutide shortage resolved on February 21, 2025, and the grace periods tied to that shortage ended on April 22, 2025 for 503A pharmacies and May 22, 2025 for 503B outsourcing facilities. The FDA says compounded drugs should only be used when a patient's needs cannot be met by an FDA-approved drug.
Does Medicare cover weight-loss GLP-1s?
Through the Medicare GLP-1 Bridge, from July 1, 2026 through December 31, 2027, eligible Part D enrollees can get Foundayo, Wegovy, or Zepbound KwikPen for weight management for a $50 monthly copayment. Eligibility depends on BMI and specific health conditions.
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